hrp0082p2-d1-534 | Puberty and Neuroendocrinology | ESPE2014

Endocrine Disruptors and Polycystic Ovary Syndrome: Phthalates

Akin Leyla , Kendirci Mustafa , Narin Figen , Kurtoglu Selim , Kondolot Meda , Saraymen Recep , Kocak Selda Ozkan , Hatipoglu Nihal , Elmali Ferhan

Background: Polycystic ovary syndrome (PCOS), characterized by hyperandrojenemia, anovulatory periods and polycystic ovaries, is a disorder in which metabolic and reproductive abnormalities overlap. The etiopathogenesis is currently unclarified. Besides the evidence of genetic causes, environmental factors are considered to be involved in development of phenotype. Phthalates are widely used industrial chemicals and have several known untoward effects on human reproductive heal...